scoper - The SCOPer package

Description

Provides a computational framework for unsupervised identification B cell clones from adaptive immune receptor repertoire sequencing (AIRR-Seq) datasets. This method is based on spectral clustering of the junction sequences of B cell receptors (BCRs, Immunoglobulins) that share the same V gene, J gene and junction length.

Spectral Clustering for clOne Partitioning (SCOPer)

References

  1. Nouri N and Kleinstein SH (2018). A spectral clustering-based method for identifying clones from high-throughput B cell repertoire sequencing data. Bioinformatics, 34(13):i341-i349.